SCHEMBL11596809

SCHEMBL11596809

CCc1c(C(C)(C)C)[c]ccc1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL980318 0.79 ESR1 (0.34)
SCHEMBL15063777 0.74 NOS3 (0.38) NOS3NOS2
SCHEMBL348335 0.74 TRPA1 (0.31)
SCHEMBL5485666 0.72
SCHEMBL8348913 0.72 NOS3 (0.36) NOS3NOS2
SCHEMBL9674011 0.71 NOS3 (0.35) NOS3NOS2
SCHEMBL10575456 0.68 KCNH2 (0.36)
SCHEMBL982496 0.68 NOS2 (0.35) NOS3NOS2
SCHEMBL983976 0.66 ALDH1A1 (0.33) NOS2
SCHEMBL983817 0.66 LTA4H (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4070383-A COPPER COMPOUND-ANIONIC SURFACTANT-ALKALI METAL COMPOUND CATALYST SYSTEM ICI AMERICAS INC. (US) 1978-01-24 US disclosed