Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782926 | 0.81 | PPARG (0.41) | ALDH1A1PPARGPPARASMN1; SMN2NR1D1 | |
| SCHEMBL8373359 | 0.81 | ALDH1A1 (0.41) | ALDH1A1PPARGPPARAMAPTLMNA | |
| SCHEMBL8371983 | 0.81 | ALDH1A1 (0.41) | ALDH1A1PPARGPPARAMAPTLMNA | |
| SCHEMBL11648038 | 0.81 | ALDH1A1 (0.41) | ALDH1A1PPARGPPARAMAPTLMNA | |
| SCHEMBL29395686 | 0.80 | RAB9A (0.45) | ALDH1A1MAPTSMN1; SMN2ITGA4ITGB7 | |
| SCHEMBL9572048 | 0.79 | ALDH1A1 (0.40) | ALDH1A1PPARGPPARAMAPTLMNA | |
| SCHEMBL4516266 | 0.75 | NPC1 (0.39) | ALDH1A1PPARGPPARAMAPTSMN1; SMN2 | |
| SCHEMBL10521236 | 0.75 | ALDH1A1 (0.41) | ALDH1A1PPARGPPARAMAPTLMNA | |
| SCHEMBL3920080 | 0.74 | GSK3B (0.40) | ALDH1A1PPARGPPARAMAPTLMNA | |
| SCHEMBL4313273 | 0.74 | MAPT (0.43) | ALDH1A1MAPTLMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193904-B1 | AMINO ACID DERIVATIVES AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4743614-A | RESTORATIVE PROPERTIES INC IMMUNODEFICIENT HOSTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0193904-A2 | Amino acid derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |