SCHEMBL9803760

SCHEMBL9803760

CCCCC[Si](CCCCC)(CCCCC)c1c(C#N)c(C#N)cc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA3 Q9Y6Q9 1/20 0.37
CLK1 P49759 1/20 0.35
DYRK1A Q13627 1/20 0.35
KDM4E B2RXH2 5/20 0.34
ALDH1A1 P00352 4/20 0.34
MAPT P10636 2/20 0.34
GAA P10253 2/20 0.34
HPGD P15428 2/20 0.34
GLA P06280 1/20 0.34
POLB P06746 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SAE1 Q9UBE0 1/20 0.34
UBA2 Q9UBT2 1/20 0.34
ALOX15 P16050 3/20 0.34
IKBKB O14920 1/20 0.33
ANPEP P15144 1/20 0.33
GRK6 P43250 1/20 0.33
CA1 P00915 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9469739 0.77 MAPT (0.42) NCOA3CLK1DYRK1AKDM4EALDH1A1
SCHEMBL29144799 0.75 HPGD (0.40) NCOA3CLK1DYRK1AKDM4EALDH1A1
SCHEMBL27779196 0.74 MAPT (0.42) NCOA3CLK1DYRK1AKDM4EALDH1A1
SCHEMBL26597967 0.73 MYB (0.40) NCOA3CLK1DYRK1AKDM4EALDH1A1
SCHEMBL31457372 0.69 CLK1 (0.49) NCOA3CLK1DYRK1AKDM4EALDH1A1
SCHEMBL28869476 0.69 CLK1 (0.49) NCOA3CLK1DYRK1AKDM4EALDH1A1
SCHEMBL9453843 0.69 CLK1 (0.45) NCOA3CLK1DYRK1AKDM4EALDH1A1
SCHEMBL27808798 0.68 LIPG (0.38) KDM4EALDH1A1MAPTGAAHPGD
SCHEMBL28171463 0.68 TLR8 (0.46) KDM4EALDH1A1MAPTGAAHPGD
SCHEMBL9602680 0.67 MAPT (0.46) KDM4EALDH1A1MAPTGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0279501-B1 NOVEL NAPHTHALOCYANINE DYE,METHOD FOR PREPARING THE SAME, AND OPTICAL INFORMATION RECORDING MEDIUM EMPLOYING THE SAME Hitachi Chemical Co., Ltd. (JP) 1991-04-03 EP claimed
EP-0279501-A1 Novel naphthalocyanine dye,method for preparing the same, and optical information recording medium employing the same Hitachi Chemical Co., Ltd. (JP) 1988-08-24 EP claimed
JP-1054069-A None JP disclosed
EP-0279501-B1 NOVEL NAPHTHALOCYANINE DYE,METHOD FOR PREPARING THE SAME, AND OPTICAL INFORMATION RECORDING MEDIUM EMPLOYING THE SAME Hitachi Chemical Co., Ltd. (JP) 1991-04-03 EP disclosed
US-4927735-A READING STABILITY HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-05-22 US disclosed
JP-S6454069-A NEW NAPHTHALOCYANINE COLORING MATTER, ITS PREPARATION, AND OPTICAL INFORMATION RECORDING MEDIUM MADE THEREFROM HITACHI CHEMICAL CO LTD 1989-03-01 JP disclosed
EP-0279501-A1 Novel naphthalocyanine dye,method for preparing the same, and optical information recording medium employing the same Hitachi Chemical Co., Ltd. (JP) 1988-08-24 EP disclosed