Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 13/20 | 0.51 |
| ▸ | ATP4B | P51164 | 13/20 | 0.51 |
| ▸ | LTA4H | P09960 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803904 | 0.80 | HPGD (0.58) | HPGD | |
| SCHEMBL1990539 | 0.79 | CETP (0.50) | ATP4AATP4BSMN1; SMN2 | |
| SCHEMBL6802249 | 0.78 | PPARG (0.57) | ATP4AATP4B | |
| SCHEMBL4744464 | 0.78 | ATP4A (0.45) | ATP4AATP4BLMNAMAPTSMN1; SMN2 | |
| SCHEMBL6806357 | 0.77 | ATP4A (0.57) | ATP4AATP4B | |
| SCHEMBL18013086 | 0.77 | MAPT (0.53) | ATP4AATP4BLTA4HKCNH2ALDH1A1 | |
| SCHEMBL4744468 | 0.77 | PPARG (0.63) | ATP4AATP4B | |
| SCHEMBL9803921 | 0.75 | KDM4E (0.42) | ATP4AATP4BLTA4HMAPT | |
| SCHEMBL8204708 | 0.74 | ALDH1A1 (0.75) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL5090074 | 0.74 | ALDH1A1 (0.75) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075300-A | Hypoglycemic and antilipemic agents | BEECHAM GROUP P.L.C. (GB) | 1991-12-24 | — | — | US | disclosed |
| EP-0356214-A2 | Thiazolidine dione derivatives | BEECHAM GROUP PLC (GB) | 1990-02-28 | — | — | EP | disclosed |