Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 12/20 | 0.45 |
| ▸ | ATP4B | P51164 | 12/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005904 | 0.82 | DRD4 (0.46) | CETPLMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL1990539 | 0.82 | CETP (0.50) | ATP4AATP4BCETPTP53SMN1; SMN2 | |
| SCHEMBL7922696 | 0.79 | PPARG (0.64) | TP53RAB9ADRD4 | |
| SCHEMBL2786491 | 0.79 | PPARG (0.53) | DRD4 | |
| SCHEMBL9005930 | 0.78 | ALDH1A1 (0.50) | LMNATP53MAPTDRD4L3MBTL1 | |
| SCHEMBL9160316 | 0.78 | PPARG (0.42) | CETPLMNATP53SMN1; SMN2DRD4 | |
| SCHEMBL7922719 | 0.78 | PPARG (0.48) | DRD4 | |
| SCHEMBL9005955 | 0.78 | ALOX5 (0.47) | LMNATP53SMN1; SMN2DRD4 | |
| SCHEMBL9803918 | 0.78 | ATP4A (0.51) | ATP4AATP4BLMNASMN1; SMN2MAPT | |
| SCHEMBL5209260 | 0.77 | PPARG (0.43) | CETPDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |