SCHEMBL9804048

SCHEMBL9804048

O=C1COc2c(ccc3ccccc23)N1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
CYP19A1 P11511 3/20 0.35
ALDH1A1 P00352 5/20 0.35
KDM4E B2RXH2 4/20 0.35
MAPT P10636 4/20 0.35
HPGD P15428 4/20 0.35
HSD17B10 Q99714 4/20 0.35
TSHR P16473 2/20 0.35
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
CBX7 O95931 1/20 0.35
CDYL2 Q8N8U2 1/20 0.35
CDYL Q9Y232 1/20 0.35
CDY1; CDY1B Q9Y6F8 1/20 0.35
PAX8 Q06710 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
GLA P06280 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-F-D-Diboa SCHEMBL4264080 0.71 TERT (0.44) POLBCYP19A1ALDH1A1KDM4EMAPT
8-Cl-D-Diboa SCHEMBL6520164 0.71 NOTUM (0.47) POLBTSHRMEN1KMT2A
7,8-Dif-D-Diboa SCHEMBL4268229 0.71 TERT (0.33) MEN1KMT2A
SCHEMBL2748218 0.69 TSHR (0.53) POLBALDH1A1KDM4EMAPTTSHR
SCHEMBL30581468 0.69 TSHR (0.53) POLBALDH1A1KDM4EMAPTTSHR
SCHEMBL86747 0.68 CYP19A1 (0.54) CYP19A1ALDH1A1KDM4EMAPTHPGD
Chrysene SCHEMBL5008949 0.66 HPRT1 (0.54) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL9804069 0.66 CYP19A1 (0.38) CYP19A1ALDH1A1KDM4EMAPTHPGD
SCHEMBL11054436 0.65 POLB (0.57) POLBALDH1A1KDM4EMAPTHPGD
SCHEMBL10907831 0.64 HTR1A (0.39) ALDH1A1KDM4EMAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026848-A Antirhinovirus agents SYNPHAR LABORATORIES INCORPORATED (CA) 1991-06-25 US disclosed