Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL86747 | 0.71 | CYP19A1 (0.54) | CYP19A1PAX8HSD17B10ALDH1A1TSHR | |
| SCHEMBL341904 | 0.68 | KDM4E (0.47) | ALDH1A1TSHRKDM4ECYP1A2MAPT | |
| SCHEMBL9804048 | 0.66 | POLB (0.36) | CYP19A1PAX8HSD17B10ALDH1A1TSHR | |
| SCHEMBL29962771 | 0.66 | KDM4E (0.50) | CYP19A1PAX8HSD17B10ALDH1A1TSHR | |
| SCHEMBL18533243 | 0.64 | CYP19A1 (0.40) | CYP19A1HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL6453627 | 0.63 | MAOA (0.46) | CYP19A1HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL21591513 | 0.62 | CA12 (0.39) | CYP19A1HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL7531559 | 0.62 | DNMT1 (0.40) | CYP19A1PAX8HSD17B10ALDH1A1TSHR | |
| SCHEMBL8641190 | 0.62 | ALOX5 (0.53) | CYP19A1PAX8HSD17B10ALDH1A1TSHR | |
| SCHEMBL9495807 | 0.62 | ALOX5 (0.45) | CYP19A1PAX8HSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | disclosed |