Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 8-F-D-Diboa SCHEMBL4264080 | 0.80 | TERT (0.44) | NOTUMTSHRAADATHTR6POLB | |
| 6,8-Dicl-D-Diboa SCHEMBL4268242 | 0.77 | SLC5A2 (0.42) | NOTUMSLC5A1SLC5A2HTR2A | |
| SCHEMBL30581468 | 0.72 | TSHR (0.53) | TSHRUSP2POLBMEN1KMT2A | |
| SCHEMBL2748218 | 0.72 | TSHR (0.53) | TSHRUSP2POLBMEN1KMT2A | |
| SCHEMBL9804048 | 0.71 | POLB (0.36) | TSHRPOLBMEN1KMT2A | |
| 7,8-Dif-D-Diboa SCHEMBL4268229 | 0.70 | TERT (0.33) | MEN1KMT2A | |
| 6-Cl-D-Diboa SCHEMBL4267274 | 0.67 | KMO (0.58) | TSHRSLC5A1SLC5A2USP2POLB | |
| SCHEMBL30871932 | 0.67 | KMO (0.48) | TSHRAADATSLC5A1SLC5A2USP2 | |
| SCHEMBL3976344 | 0.66 | PARP1 (0.54) | NOTUMMEN1KMT2A | |
| SCHEMBL14302362 | 0.64 | HTR6 (0.64) | TSHRHTR6POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059850-A1 | PHYTOTOXIC HALOGENATED DERIVATIVES OF BENZOXAZINONES | UNIVERSIDAD DE CÁDIZ (ES) | 2011-03-10 | — | — | US | claimed |