Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6484123 | 0.82 | LMNA (0.43) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9877558 | 0.78 | NPC1 (0.56) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL10509681 | 0.77 | DAGLA (0.46) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL10515147 | 0.77 | DAGLA (0.64) | KMT2AMEN1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL11032320 | 0.76 | MEN1 (0.51) | KMT2AMEN1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL28248398 | 0.76 | NPC1 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9804162 | 0.75 | KMT2A (0.43) | KMT2AMEN1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL9803998 | 0.75 | MEN1 (0.46) | KMT2AMEN1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL9804140 | 0.75 | MAOA (0.45) | KMT2AMEN1HTT | |
| SCHEMBL9804051 | 0.74 | HTT (0.47) | KMT2AMEN1ALDH1A1NR1I2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | claimed |
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | disclosed |