Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 8/20 | 0.38 |
| ▸ | LTA4H | P09960 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436495 | 0.82 | CHRNB4 (0.53) | KCNH2 | |
| SCHEMBL14499366 | 0.81 | CYP1A2 (0.39) | NR1I2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL9436119 | 0.80 | PTGS2 (0.40) | KMT2AMEN1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL11032320 | 0.77 | MEN1 (0.51) | KMT2AMEN1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL10642084 | 0.76 | ALDH1A1 (0.55) | KMT2AALDH1A1CNR2LTA4HMAPT | |
| SCHEMBL9803998 | 0.76 | MEN1 (0.46) | KMT2AMEN1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL14499365 | 0.76 | CYP1A2 (0.41) | NR1I2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL9804050 | 0.75 | KMT2A (0.42) | KMT2AMEN1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL9804051 | 0.75 | HTT (0.47) | KMT2AMEN1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL9804036 | 0.75 | MEN1 (0.47) | KMT2AMEN1ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | claimed |
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | disclosed |
| EP-0335636-A1 | Antiviral compounds | SYNPHAR LABORATORIES INC. (CA) | 1989-10-04 | — | — | EP | disclosed |