Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 9/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171872 | 0.79 | KDM4E (0.50) | CYP1A2CYP2C9CYP2C19TDP1 | |
| SCHEMBL3771417 | 0.79 | TDP1 (0.56) | CYP1A2CYP2C9CYP2C19TDP1 | |
| SCHEMBL8571428 | 0.77 | TSHR (0.53) | CYP1A2CYP2C9CYP2C19TDP1 | |
| SCHEMBL8573729 | 0.75 | HDAC8 (0.44) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9804236 | 0.73 | ACHE (0.49) | ACHECYP1A2CYP2C9CYP2C19CES1 | |
| SCHEMBL9000245 | 0.72 | ALDH1A1 (0.62) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8893799 | 0.72 | TSHR (0.61) | — | |
| SCHEMBL30539184 | 0.72 | ALDH1A1 (0.62) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5806651 | 0.69 | HPGD (0.62) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5806652 | 0.69 | HPGD (0.62) | CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |