Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3255990 | 0.79 | ALDH1A1 (0.52) | TSHRCTNNB1WNT3ANPC1CYP1A2 | |
| SCHEMBL7153475 | 0.79 | KDM4E (0.50) | TSHRCTNNB1WNT3ANPC1CYP1A2 | |
| SCHEMBL29746867 | 0.77 | TSHR (0.53) | TSHRCTNNB1WNT3ANPC1CYP1A2 | |
| SCHEMBL703172 | 0.76 | TSHR (0.45) | TSHRCTNNB1WNT3ANPC1CYP1A2 | |
| SCHEMBL24401018 | 0.75 | ALOX5 (0.50) | TSHRNPC1CYP1A2CYP2C9HPGD | |
| SCHEMBL758623 | 0.74 | CTNNB1 (0.44) | ACHETSHRCTNNB1WNT3AKIF11 | |
| SCHEMBL7766618 | 0.74 | COXFA4 (0.49) | ACHEBACE1NPC1HPGDRAB9A | |
| SCHEMBL9315164 | 0.74 | ACHE (0.40) | ACHECES1 | |
| SCHEMBL10419639 | 0.73 | CTNNB1 (0.50) | TSHRCTNNB1WNT3ANPC1CYP1A2 | |
| SCHEMBL9804240 | 0.73 | ACHE (0.45) | ACHECES1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |