SCHEMBL9804371

SCHEMBL9804371

C[Si](C)(C)N1C(=O)CCC1=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.32
BRD2 P25440 1/20 0.32
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL11443295 0.89
SCHEMBL9804370 0.88 BRD4 (0.40) BRD4BRD2
SCHEMBL22680926 0.73
SCHEMBL22680928 0.70 BRD4 (0.40) BRD4BRD2
SCHEMBL21969141 0.69 LMNA (0.31)
SCHEMBL11449684 0.67
SCHEMBL19923660 0.66 PLA2G7 (0.33) BRD4BRD2
SCHEMBL6709579 0.63 PARL (0.33)
SCHEMBL2696612 0.63
SCHEMBL9020270 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034394-B1 PROCESS FOR THE PREPARATION OF 3'-BROMOSUBSTITUTED DEACETOXYCEPHALOSPORANIC ACID SULPHOXIDE DERIVATIVES GIST-BROCADES N.V. (NL) 1984-08-01 EP claimed
US-4366315-A Process for preparing 3'bromo-desacetoxycephalosporanic acid sulfoxide compounds GIST-BROCADES N.V. (NL) 1982-12-28 US claimed
EP-0034394-A2 Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives GIST-BROCADES N.V. (NL) 1981-08-26 EP claimed
US-20230387464-A1 Nonaqueous Electrolytic Solution and Nonaqueous Electrolytic Solution Battery MU IONIC SOLUTIONS CORPORATION (JP) 2023-11-30 US disclosed
US-20230387464-A1 Nonaqueous Electrolytic Solution and Nonaqueous Electrolytic Solution Battery MU IONIC SOLUTIONS CORPORATION (JP) 2023-11-30 US disclosed
CN-111370764-B Non-aqueous electrolyte and lithium ion battery containing same 珠海市赛纬电子材料股份有限公司 2022-09-09 CN disclosed
CN-111370764-A Non-aqueous electrolyte and lithium ion battery containing same 珠海市赛纬电子材料股份有限公司 2020-07-03 CN disclosed
US-20200144074-A1 PROCESS FOR THE ETCHING METAL- OR SEMIMETAL-CONTAINING MATERIALS BASF SE (DE) 2020-05-07 US disclosed
EP-0413464-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-02-20 EP disclosed
EP-0413465-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-02-20 EP disclosed
US-4981827-A Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-01 US disclosed
US-4282145-A Process for the preparation of azetidines GIST-BROCADES N.V. (NL) 1981-08-04 US disclosed
US-4223134-A Process for preparing cephalosporin antibiotics ELI LILLY AND COMPANY (US) 1980-09-16 US disclosed
US-4159266-A AZETIDINONE SULFINIC ACID DERIVATIVES ELI LILLY AND COMPANY (US) 1979-06-26 US disclosed
US-4148817-A Process and intermediates for preparing cephalosporin antibiotics ELI LILLY AND COMPANY (US) 1979-04-10 US disclosed
US-4107432-A ANTIBIOTICS MERCK & CO., INC. (US) 1978-08-15 US disclosed
US-4061630-A 7-Substituted-ureido-3-carbamoyloxymethyl cephalosporin antibiotics ELI LILLY AND COMPANY (US) 1977-12-06 US disclosed
US-4058661-A 7-Diacyl cephalosporins MERCK & CO., INC. (US) 1977-11-15 US disclosed
US-4052387-A METHOD OF PREPARATION OF 3-METHYLENECEPHAMS ELI LILLY AND COMPANY (US) 1977-10-04 US disclosed
US-4014873-A Process for the production of 7-acylamidocephalosporins MERCK & CO., INC. (US) 1977-03-29 US disclosed