SCHEMBL19923660

SCHEMBL19923660

CN1CC(=O)N([Si](C)(C)C)C1=O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 1/20 0.33
KMT2A Q03164 1/20 0.32
CRBN Q96SW2 1/20 0.31
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
TAS2R8 Q9NYW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923649 0.76 KMT2A (0.33) PLA2G7KMT2A
SCHEMBL19923645 0.74 PLA2G7 (0.33) PLA2G7KMT2A
SCHEMBL19923760 0.71 GRM4 (0.33)
SCHEMBL19923761 0.71 F2 (0.32)
SCHEMBL19923593 0.70 PLA2G7 (0.43) PLA2G7KMT2ABRD4
SCHEMBL27030667 0.69 PLA2G7 (0.36) PLA2G7KMT2ACRBNBRD4BRD2
SCHEMBL22070 0.69
Bromide SCHEMBL28907673 0.67 PLA2G7 (0.35) PLA2G7KMT2ACRBNBRD4BRD2
SCHEMBL1685396 0.67 PLA2G7 (0.35) PLA2G7KMT2ACRBNBRD4BRD2
Hydrochloric Acid SCHEMBL28447867 0.67 PLA2G7 (0.35) PLA2G7KMT2ACRBNBRD4BRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN PLA2G7 2819/4885KMT2A 1080/4885CRBN 1348/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM PLA2G7 2655/4885KMT2A 999/4885CRBN 1559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.