Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804740 | 0.84 | KCNH3 (0.36) | USP2RAB9ACYP19A1 | |
| SCHEMBL9804704 | 0.80 | KDM4E (0.34) | RORCKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL9804885 | 0.77 | KDM4E (0.32) | RORCKDM4EALDH1A1HPGD | |
| SCHEMBL9804872 | 0.75 | TERT (0.38) | RORCKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL9804963 | 0.71 | CYP19A1 (0.42) | KDM4EALDH1A1HPGDKMT2ACYP19A1 | |
| SCHEMBL9804889 | 0.70 | CYP1A2 (0.37) | KDM4E | |
| SCHEMBL11100258 | 0.69 | RAB9A (0.39) | RORCKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL9804742 | 0.69 | CYP19A1 (0.39) | KDM4EALDH1A1KMT2ACYP19A1 | |
| SCHEMBL9804782 | 0.69 | CYP19A1 (0.39) | KDM4EALDH1A1HPGDCYP19A1 | |
| SCHEMBL9804805 | 0.68 | CYP19A1 (0.40) | KDM4EALDH1A1HPGDKMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276920-B1 | (2-CYANO-2-(PHENYL OR NAPHTHYL)-2-SUBSTITUTED-ETHYL) PYRAZINES, PYRIMIDINES AND PYRIDAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |