Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.69 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.59 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.59 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.59 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.59 |
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | FBP1 | P09467 | 1/20 | 0.59 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.59 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL9805161 | 0.87 | DOT1L (0.68) | ADORA1SMN1; SMN2EHMT2NNMTADORA3 | |
| SCHEMBL1858296 | 0.85 | MARS1 (0.75) | MARS1PLA2G2AP2RY1ADORA1SRC | |
| SCHEMBL6408975 | 0.85 | MARS1 (0.80) | MARS1P2RY1ADORA1SRCP2RY2 | |
| SCHEMBL6408983 | 0.85 | MARS1 (0.80) | MARS1P2RY1ADORA1SRCP2RY2 | |
| SCHEMBL2761284 | 0.82 | MARS1 (0.74) | MARS1PLA2G2AP2RY1ADORA1SRC | |
| SCHEMBL7757016 | 0.82 | MARS1 (0.73) | MARS1P2RY1ADORA1SRCP2RY2 | |
| SCHEMBL3014292 | 0.82 | MARS1 (1.00) | MARS1EHMT2NNMTNSD2PCMT1 | |
| SCHEMBL583457 | 0.82 | MARS1 (1.00) | MARS1EHMT2NNMTNSD2PCMT1 | |
| SCHEMBL8846496 | 0.82 | MARS1 (0.73) | MARS1PLA2G2AP2RY1ADORA1SRC | |
| SCHEMBL2463542 | 0.81 | PRKACA (0.73) | MARS1P2RY1ADORA1SRCP2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043270-A | Genetic engineering to produce polypeptide drugs, amplification | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1991-08-27 | — | — | US | disclosed |
| WO-1990012025-A1 | INTRONIC OVEREXPRESSION VECTORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1990-10-18 | — | — | WO | disclosed |