Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PYGB | P11216 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805128 | 0.82 | GSK3B (0.49) | GSK3BHPGDADORA2AADORA3ADORA1 | |
| SCHEMBL9805184 | 0.82 | GSK3B (0.38) | GSK3BHPGDADORA2AADORA3ADORA1 | |
| SCHEMBL9805171 | 0.73 | ADK (0.55) | ADORA2AADORA3ADORA1ADORA2BMEN1 | |
| SCHEMBL3236739 | 0.70 | GSK3B (0.53) | GSK3BMEN1KMT2AADKPNP | |
| SCHEMBL6885781 | 0.69 | GSK3B (0.52) | GSK3BADKTSHRPYGB | |
| SCHEMBL6886938 | 0.69 | XDH (0.48) | GSK3BADK | |
| SCHEMBL31338626 | 0.66 | GSK3B (0.48) | GSK3BMEN1KMT2AADKPNP | |
| SCHEMBL4286250 | 0.65 | GSK3B (0.47) | GSK3BADKTSHR | |
| SCHEMBL6889028 | 0.65 | GSK3B (0.47) | GSK3BADKTSHR | |
| SCHEMBL5697577 | 0.65 | GSK3B (0.47) | GSK3BADKTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041542-A | Antitumor-anticarcinogenic agents | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1991-08-20 | — | — | US | disclosed |