SCHEMBL9805740

SCHEMBL9805740

Cc1ccc(N(C)C(=O)N(C)Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
RAB9A P51151 2/20 0.47
TSHR P16473 1/20 0.44
HSD17B1 P14061 3/20 0.44
HSD17B2 P37059 3/20 0.44
MAPT P10636 2/20 0.43
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 2/20 0.39
GPBAR1 Q8TDU6 2/20 0.39
MCOLN3 Q8TDD5 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12550524 0.87 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2RAB9ATSHRHSD17B1
SCHEMBL11046065 0.83 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2RAB9ATSHRHSD17B1
SCHEMBL8924930 0.79 POLB (0.50) ALDH1A1SMN1; SMN2RAB9ATSHRMEN1
SCHEMBL11616779 0.78 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2RAB9ATSHRHSD17B1
SCHEMBL11281321 0.76 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2RAB9ATSHRHSD17B1
SCHEMBL2089211 0.76 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2RAB9ATSHRHSD17B1
SCHEMBL2069525 0.76 ALDH1A1 (0.72) ALDH1A1SMN1; SMN2RAB9ATSHRHSD17B1
SCHEMBL2089214 0.76 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2RAB9ATSHRHSD17B1
SCHEMBL8014181 0.75 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2RAB9ATSHRHSD17B1
SCHEMBL17460823 0.75 ACHE (0.56) ALDH1A1SMN1; SMN2RAB9AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5032488-A Method of metalizing a surface using a mixture of olefin and dibenzalacetone palladium complex CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4826927-A LAMINATING RESINS, ELECTRO-RESINS CIBA-GEIGY CORPORATION (US) 1989-05-02 US disclosed