Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.91 |
| ▸ | HPGD | P15428 | 6/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL6249450 | 0.97 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL9183232 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL3399561 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL217212 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL299753 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL12477386 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL224818 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL106935 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL10490726 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL455422 | 0.95 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116344842-A | Carbon-supported low-platinum alloy nanocrystalline catalyst, preparation method and application thereof, and fuel cell | 北京化工大学 | 2023-06-27 | — | — | CN | claimed |
| EP-2658895-B1 | ALKYLENE OXIDE POLYMERIZATION USING A DOUBLE METAL CYANIDE CATALYST COMPLEX AND A MAGNESIUM, GROUP 3-GROUP 15 METAL OR LANTHANIDE SERIES METAL COMPOUND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-06-23 | — | — | EP | claimed |
| US-10233284-B2 | Alkylene oxide polymerization using a double metal cyanide catalyst complex and a magnesium, group 3-group 15 metal or lanthanide series metal compound | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-03-19 | — | — | US | claimed |
| US-20170101506-A1 | ALKYLENE OXIDE POLYMERIZATION USING A DOUBLE METAL CYANIDE CATALYST COMPLEX AND A MAGNESIUM, GROUP 3 - GROUP 15 METAL OR LANTHANIDE SERIES METAL COMPOUND | DOW GLOBAL TECHNOLOGIES LLC | 2017-04-13 | — | — | US | claimed |
| US-20140031328-A1 | Gallium compounds and methods of use to treat inflammatory bowel disease | BERNSTEIN LAWRENCE RICHARD (US) | 2014-01-30 | — | — | US | claimed |
| US-20110021484-A1 | Gallium compounds and methods of use to treat inflammatory bowel disease | BERNSTEIN LAWRENCE RICHARD | 2011-01-27 | — | — | US | claimed |
| EP-2262509-A2 | GALLIUM COMPOUNDS AND METHODS OF USE TO TREAT INFLAMMATORY BOWEL DISEASE | Bernstein, Lawrence (US) | 2010-12-22 | — | — | EP | claimed |
| WO-2009111681-A2 | GALLIUM COMPOUNDS AND METHODS OF USE TO TREAT INFLAMMATORY BOWEL DISEASE | BERNSTEIN LAWRENCE (US) | 2009-09-11 | — | — | WO | claimed |
| EP-4423168-B1 | POLYETHER POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-12-10 | — | — | EP | disclosed |
| EP-4638556-A1 | ALKOXYLATION PROCESSES USING PHOSPHORUS AND DOUBLE METAL CYANIDE CATALYSTS | Dow Global Technologies LLC (US) | 2025-10-29 | — | — | EP | disclosed |
| US-20250115711-A1 | POLYETHER POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-04-10 | — | — | US | disclosed |
| US-12201971-B2 | Polyether polymerization process | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-01-21 | — | — | US | disclosed |
| US-20240392068-A1 | POLYETHER POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-11-28 | — | — | US | disclosed |
| US-12152104-B2 | Polyether polymerization process | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-11-26 | — | — | US | disclosed |
| EP-2262509-A2 | GALLIUM COMPOUNDS AND METHODS OF USE TO TREAT INFLAMMATORY BOWEL DISEASE | Bernstein, Lawrence (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009111681-A2 | GALLIUM COMPOUNDS AND METHODS OF USE TO TREAT INFLAMMATORY BOWEL DISEASE | BERNSTEIN LAWRENCE (US) | 2009-09-11 | — | — | WO | disclosed |
| EP-0242693-B1 | ANTIFOULANTS FOR THERMAL CRACKING PROCESSES | PHILLIPS PETROLEUM COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4804487-A | ORGANIC GALLIUM AND/OR TIN COMPOUNDS PREVENT FORMATION OF CARBON DEPOSITS | PHILLIPS PETROLEUM COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0242693-A1 | Antifoulants for thermal cracking processes | PHILLIPS PETROLEUM COMPANY (US) | 1987-10-28 | — | — | EP | disclosed |
| US-4666583-A | COMPOUNDS OF GALLIUM WITH TIN OR ANTIMONY | PHILLIPS PETROLEUM COMPANY (US) | 1987-05-19 | — | — | US | disclosed |