Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL10731909 | 0.82 | HIF1A (0.47) | EPHX2FAAHCNR1CNR2SOAT2 | |
| Iodide SCHEMBL11070153 | 0.82 | HIF1A (0.47) | EPHX2FAAHCNR1CNR2SOAT2 | |
| Iodide SCHEMBL19032656 | 0.82 | HIF1A (0.47) | EPHX2FAAHCNR1CNR2SOAT2 | |
| SCHEMBL9631619 | 0.81 | NR1I2 (0.40) | EPHX2FAAHCNR1CNR2SOAT2 | |
| Iodide SCHEMBL11062979 | 0.81 | SOAT2 (0.46) | EPHX2FAAHCNR1CNR2SOAT2 | |
| Iodide SCHEMBL11062977 | 0.81 | SOAT2 (0.46) | EPHX2FAAHCNR1CNR2SOAT2 | |
| Iodide SCHEMBL11067074 | 0.80 | EPHX2 (0.45) | EPHX2FAAHCNR1CNR2PPARA | |
| Bromide SCHEMBL8990164 | 0.80 | EPHX2 (0.45) | EPHX2FAAHCNR1CNR2PPARA | |
| Iodide SCHEMBL11067078 | 0.80 | EPHX2 (0.45) | EPHX2FAAHCNR1CNR2PPARA | |
| Phenylmethanesulfonic Acid SCHEMBL6230993 | 0.76 | CA2 (0.41) | FAAHALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170048-B1 | ALIPHATIC THIOETHERS | CIBA-GEIGY AG (CH) | 1991-04-17 | — | — | EP | disclosed |
| EP-0170048-A2 | Aliphatic thioethers | CIBA-GEIGY AG (CH) | 1986-02-05 | — | — | EP | disclosed |