Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985762 | 0.86 | TSHR (0.57) | ALDH1A1GAASMN1; SMN2MAPK1TSHR | |
| SCHEMBL954897 | 0.86 | ALDH1A1 (0.57) | ALDH1A1GAASMN1; SMN2MAPTLMNA | |
| SCHEMBL30736569 | 0.86 | ALDH1A1 (0.57) | ALDH1A1GAASMN1; SMN2MAPTLMNA | |
| SCHEMBL4135400 | 0.83 | THRB (0.55) | ALDH1A1GAASMN1; SMN2CACNA1FCACNA1D | |
| SCHEMBL7463516 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1GAASMN1; SMN2MAPK1TSHR | |
| SCHEMBL27580106 | 0.82 | TSHR (0.49) | ALDH1A1SMN1; SMN2THRBTSHRDHODH | |
| SCHEMBL12952931 | 0.80 | ERCC5 (0.58) | ALDH1A1GAASMN1; SMN2TSHRMAPT | |
| SCHEMBL11156928 | 0.80 | NLRP3 (0.47) | ALDH1A1GAASMN1; SMN2TSHRLMNA | |
| SCHEMBL31245529 | 0.79 | HPGD (0.53) | ALDH1A1SMN1; SMN2MAPTPOLBKMT2A | |
| SCHEMBL15060376 | 0.79 | MAPT (0.54) | ALDH1A1GAASMN1; SMN2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | disclosed |