Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634832 | 0.86 | TDP1 (0.50) | CACNA1CRAB9ACES2ACHECES1 | |
| SCHEMBL2606755 | 0.86 | KMT2A (0.55) | RAB9ACES2ACHECES1L3MBTL1 | |
| SCHEMBL31016519 | 0.86 | KMT2A (0.55) | RAB9ACES2ACHECES1L3MBTL1 | |
| Alcohol SCHEMBL28003927 | 0.83 | MEN1 (0.52) | RAB9ACES2ACHECES1L3MBTL1 | |
| SCHEMBL1716245 | 0.81 | CES2 (0.46) | CACNA1CRAB9AGPR35CES2ACHE | |
| SCHEMBL16585208 | 0.81 | LMNA (0.44) | CACNA1CRAB9ACES2ACHECES1 | |
| SCHEMBL31016515 | 0.81 | LMNA (0.44) | CACNA1CRAB9ACES2ACHECES1 | |
| SCHEMBL1500911 | 0.78 | MEN1 (0.46) | RAB9AL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL3962914 | 0.78 | CYP1A2 (0.51) | RAB9AGPR35L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL9780752 | 0.78 | NPC1 (0.48) | RAB9AGPR35L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | disclosed |