Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806508 | 0.86 | MAPT (0.54) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL9806523 | 0.86 | MAPT (0.50) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL9806507 | 0.80 | MAPT (0.47) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL30593451 | 0.79 | PTGS2 (0.71) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL11344390 | 0.79 | PTGS2 (0.71) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL19065779 | 0.78 | MAPT (0.79) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL13465152 | 0.76 | MT-CO2 (0.73) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL30593456 | 0.76 | MT-CO2 (0.73) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL9806542 | 0.75 | PTGS2 (0.66) | MAPTALOX15PTGS2KMT2AMEN1 | |
| SCHEMBL9806533 | 0.75 | MAPT (0.52) | MAPTALOX15KDM4EPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | claimed |
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | disclosed |