Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 9/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | TTR | P02766 | 1/20 | 0.73 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.73 |
| ▸ | PGR | P06401 | 1/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | AR | P10275 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30593456 | 1.00 | MT-CO2 (0.73) | MT-CO2PTGS2MAPTMEN1LMNA | |
| SCHEMBL27937437 | 0.87 | MT-CO2 (0.68) | MT-CO2PTGS2MAPTMEN1LMNA | |
| Tolfenamic Acid SCHEMBL8060884 | 0.84 | MT-CO2 (1.00) | MT-CO2PTGS2MAPTMEN1LMNA | |
| Tolfenamic Acid SCHEMBL29484181 | 0.84 | MT-CO2 (1.00) | MT-CO2PTGS2MAPTMEN1LMNA | |
| SCHEMBL12608896 | 0.84 | MT-CO2 (0.77) | MT-CO2PTGS2MAPTMEN1LMNA | |
| Tolfenamic Acid SCHEMBL29389998 | 0.84 | MT-CO2 (1.00) | MT-CO2PTGS2MAPTMEN1LMNA | |
| Tolfenamic Acid SCHEMBL25190 | 0.84 | MT-CO2 (1.00) | MT-CO2PTGS2MAPTMEN1LMNA | |
| SCHEMBL11451926 | 0.84 | PTGS2 (0.72) | MT-CO2PTGS2MAPTMEN1LMNA | |
| SCHEMBL11344390 | 0.84 | PTGS2 (0.71) | MT-CO2PTGS2MAPTMEN1LMNA | |
| SCHEMBL30593451 | 0.84 | PTGS2 (0.71) | MT-CO2PTGS2MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4357346-A1 | EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Coval Biopharma (Shanghai) Co., Ltd. (CN) | 2024-04-24 | — | — | EP | disclosed |
| US-20120263650-A1 | NITROXIDE MODIFIED NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND USES THEREOF IN THE TREATMENT AND PREVENTION OF DISEASES OR DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120263650-A1 | NITROXIDE MODIFIED NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND USES THEREOF IN THE TREATMENT AND PREVENTION OF DISEASES OR DISORDERS | NOS1, NOS3, PTGS1 | MT-CO2 3323/4885PTGS2 12/4885MAPT 4694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.