Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806521 | 0.89 | FTO (0.48) | PTGS2MAPTMETTL3KMT2AHPGD | |
| SCHEMBL9806524 | 0.87 | METTL3 (0.47) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL9806507 | 0.85 | MAPT (0.47) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL9806512 | 0.81 | PTGS2 (0.61) | PTGS2MAPTALOX15METTL3KMT2A | |
| SCHEMBL16656521 | 0.79 | PTGS2 (0.66) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL9806548 | 0.78 | CLCN2 (0.44) | PTGS2MAPTKDM4EPOLBMETTL3 | |
| SCHEMBL9551829 | 0.77 | PTGS2 (0.46) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL6808925 | 0.71 | PTGS2 (0.62) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL9806510 | 0.70 | FTO (0.59) | PTGS2METTL3KMT2AMEN1AKR1B10 | |
| SCHEMBL7350437 | 0.69 | PTGS2 (0.55) | PTGS2MAPTMETTL3KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | claimed |