SCHEMBL9807147

SCHEMBL9807147

CN(Cc1ccc(Cl)cc1)c1cccc(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.50
CYP3A4 P08684 1/20 0.46
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
NLRP3 Q96P20 1/20 0.42
PDK2 Q15119 1/20 0.41
PDK4 Q16654 1/20 0.41
PPARA Q07869 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
TAAR1 Q96RJ0 2/20 0.41
HTR7 P34969 1/20 0.40
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
PYCR1 P32322 1/20 0.39
HDAC1 Q13547 1/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10907115 0.85 ALDH1A1 (0.55) ALDH1A1TSHRCYP3A4LMNAHTR7
SCHEMBL27998959 0.82 POLB (0.62) ALDH1A1LMNAPOLBHTTRAB9A
SCHEMBL10464181 0.81 PPARA (0.44) LMNAPOLBPPARATAAR1HTR7
SCHEMBL9807149 0.79 CRHBP (0.57) ALDH1A1TSHRLMNAPOLBHTT
SCHEMBL10690742 0.79 PPARA (0.61) ALDH1A1LMNAPOLBPPARAHTT
SCHEMBL11135166 0.75 TAAR1 (0.54) ALDH1A1TSHRTAAR1HTR7MAPT
SCHEMBL22166480 0.73 ALDH1A1 (0.63) ALDH1A1TSHRCYP3A4LMNAHTR7
SCHEMBL5742167 0.73 ALDH1A1 (0.68) ALDH1A1TSHRCYP3A4LMNAHTR7
SCHEMBL4349572 0.73 ALDH1A1 (0.68) ALDH1A1TSHRCYP3A4LMNAHTR7
SCHEMBL17243689 0.72 HSD17B1 (0.43) TSHRPYCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5041665-A Dropwise adding solution of hydroxycyclobutenedione derivative to alcohol solution of aniline derivative FUJI XEROX CO., LTD. (JP) 1991-08-20 US disclosed