Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.61 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.53 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687046 | 0.87 | PPARA (0.62) | PPARAMEP1BKMT2AMEN1RXRA | |
| SCHEMBL10373059 | 0.82 | RXRA (0.58) | KMT2AMEN1NR4A2RXRARXRB | |
| SCHEMBL10689680 | 0.79 | LTB4R2 (0.49) | PPARAMEP1AMEP1BKMT2AMEN1 | |
| SCHEMBL9807147 | 0.79 | ALDH1A1 (0.50) | PPARAKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9807149 | 0.78 | CRHBP (0.57) | ALDH1A1POLBRAB9ALMNAHTT | |
| SCHEMBL27998959 | 0.77 | POLB (0.62) | KMT2AMEN1ALDH1A1POLBRAB9A | |
| SCHEMBL3599505 | 0.77 | HDAC1 (0.59) | PPARAKMT2AMEN1RXRARXRB | |
| SCHEMBL1574123 | 0.77 | PPARA (0.50) | PPARAKMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL13064484 | 0.77 | MEN1 (0.78) | KMT2AMEN1ALDH1A1TAS2R14CXCR3 | |
| SCHEMBL10464181 | 0.76 | PPARA (0.44) | PPARAPOLBLMNALTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |