Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28890126 | 0.89 | AKR1C1 (0.46) | HSD11B1AKR1C1TSHRTHRBTDP1 | |
| SCHEMBL28404526 | 0.88 | CES2 (0.41) | TP53LMNA | |
| SCHEMBL29031869 | 0.88 | ALOX15 (0.44) | HSD11B1TSHRLMNA | |
| SCHEMBL29031878 | 0.88 | ALDH1A1 (0.44) | HSD11B1THRBTDP1LMNA | |
| SCHEMBL28472946 | 0.82 | CA1 (0.50) | HSD11B1THRB | |
| SCHEMBL29031873 | 0.82 | CES2 (0.47) | TSHRTHRB | |
| SCHEMBL28404806 | 0.76 | KMT2A (0.44) | TDP1 | |
| SCHEMBL30472345 | 0.71 | HCAR3 (0.44) | TP53 | |
| SCHEMBL29031880 | 0.71 | HCAR3 (0.44) | TP53 | |
| SCHEMBL10776105 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985533-A | Termotropic liquid-crystalline aromatic polyester from hydroquinone/substituted hydroquinone mixture | MONTEDISON S.P.A. (IT) | 1991-01-15 | — | — | US | disclosed |
| US-4912193-A | Controlling concentration | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |
| EP-0311389-A2 | Thermotropic liquid-crystalline aromatic polyesters | Montedison S.p.A. (IT) | 1989-04-12 | — | — | EP | disclosed |
| US-4801677-A | Thermotropic aromatic polyester with high thermal stability | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-31 | — | — | US | disclosed |