SCHEMBL9807235

CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	EPHA2	P29317	2/20	0.64

▸	NMUR2	Q9GZQ4	4/20	0.57

▸	NMUR1	Q9HB89	4/20	0.57

▸	OPRM1	P35372	7/20	0.56

▸	OPRD1	P41143	1/20	0.56

▸	SLC6A2	P23975	1/20	0.56

▸	OPRK1	P41145	6/20	0.56

▸	NPY1R	P25929	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9807253	0.95	EPHA2 (0.58)	EPHA2NMUR2NMUR1OPRM1OPRD1
SCHEMBL9807269	0.93	EPHA2 (0.63)	EPHA2NMUR2NMUR1SLC6A2NPY1R
SCHEMBL9691456	0.91	EPHA2 (0.61)	EPHA2OPRM1OPRK1
SCHEMBL9807257	0.91	NTSR1 (0.62)	EPHA2NPY1R
SCHEMBL29821642	0.90	EPHA2 (0.59)	EPHA2NMUR2NMUR1OPRM1OPRD1
SCHEMBL9807306	0.89	EPHA2 (0.62)	EPHA2NMUR2NMUR1OPRM1OPRK1
SCHEMBL9807252	0.89	EPHA2 (0.62)	EPHA2NMUR2NMUR1OPRM1OPRK1
SCHEMBL29769812	0.88	EPHA2 (0.56)	EPHA2NMUR2NMUR1OPRM1OPRD1
SCHEMBL29503865	0.88	EPHA2 (0.58)	EPHA2NMUR2NMUR1OPRM1OPRD1
SCHEMBL9807262	0.88	EPHA2 (0.61)	EPHA2NMUR2NMUR1NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0146266-B1	ENZYME-RESISTANT IMMUNOMODULATORY PEPTIDES	ORTHO PHARMACEUTICAL CORPORATION (US)	1991-05-22	—	—	EP	disclosed
EP-0146266-A2	Enzyme-resistant immunomodulatory peptides	ORTHO PHARMACEUTICAL CORPORATION (US)	1985-06-26	—	—	EP	disclosed