Sugi Predict

Sugi Predict / Compounds / SCHEMBL98076

SCHEMBL98076

SCHEMBL98076

CC(C)(C)c1cc(CCl)cc(C(C)(C)C)c1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 10/20 0.59
▸ GAA P10253 5/20 0.59
▸ TSHR P16473 4/20 0.59
▸ LMNA P02545 3/20 0.59
▸ MAPK1 P28482 3/20 0.57
▸ MEN1 O00255 3/20 0.57
▸ KMT2A Q03164 3/20 0.57
▸ CYP1A2 P05177 2/20 0.57
▸ CYP3A4 P08684 2/20 0.57
▸ BLM P54132 2/20 0.57
▸ ATM Q13315 2/20 0.57
▸ HIF1A Q16665 2/20 0.57
▸ NPSR1 Q6W5P4 2/20 0.57
▸ ALOX15 P16050 2/20 0.57
▸ GMNN O75496 1/20 0.57
▸ GABBR2 O75899 1/20 0.57
▸ TP53 P04637 1/20 0.57
▸ CYP2C9 P11712 1/20 0.57
▸ NFKB1 P19838 1/20 0.57
▸ CYP2C19 P33261 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL7903511 0.94 ALDH1A1 (0.53) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL10821976 0.88 CYP2C9 (0.57) ALDH1A1GAATSHRLMNAMAPK1
Phenol SCHEMBL28274107 0.87 MEN1 (0.53) ALDH1A1GAATSHRLMNAMAPK1
Pyridine SCHEMBL11852633 0.86 ALDH1A1 (0.46) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL10822059 0.85 HSPA5 (0.64) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL42656 0.84 ALDH1A1 (0.64) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL11408652 0.83 ALDH1A1 (0.43) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL26071953 0.83 MEN1 (0.49) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL30255512 0.83 MEN1 (0.49) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL10821960 0.83 ALDH1A1 (0.55) ALDH1A1GAATSHRLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111100384-A Novel hindered phenol-containing silane coupling agent modified calcium carbonate polyolefin and preparation method thereof 贵州师范大学 2020-05-05 — — CN claimed
CN-109320767-A A kind of novel silane coupler and its preparation method and application containing hindered phenol 联塑科技发展(贵阳)有限公司 2019-02-12 — — CN claimed
CN-108440790-A A kind of novel antioxygen silane coupling agent and preparation method thereof containing hindered phenol structure 贵州师范大学 2018-08-24 — — CN claimed
CN-104744813-B A kind of preparation method and application of Hinered phenols quaternary salt modified montmorillonoid synergistic halogen-free expanded flame-retardant agent 贵州师范大学 2016-09-14 — — CN claimed
CN-105505525-A Phenolic amine antioxidant and preparation method and application thereof NINGBO INST MAT TECH & ENG CAS 2016-04-20 — — CN claimed
CN-104744813-A Preparation method and application of hindered phenol quaternary phosphonium salt-modified montmorillonite-synergistic halogen-free intumescent flame retardant UNIV GUIZHOU NORMAL 2015-07-01 — — CN claimed
CN-104592643-A Polyolefin containing hindered phenol phosphonium salt modified montmorillonite antioxidant as well as preparation method of polyolefin UNIV GUIZHOU NORMAL 2015-05-06 — — CN claimed
CN-104497563-A Hindered phenol quaternary phosphine salt modified montmorillonoid antioxidant-containing polyamide and preparation method thereof UNIV GUIZHOU NORMAL 2015-04-08 — — CN claimed
US-20110136748-A1 NOVEL GLUCOPYRANOSE DERIVATIVES, PREPARATION THEREOF, AND BIOLOGICAL USES THEREOF VACHY ROBERT 2011-06-09 — — US claimed
US-4308407-A Chemical process ETHYL CORPORATION (US) 1981-12-29 — — US claimed
US-4091225-A ALKYLATION, REDUCTION, TRANSESTERIFICATION THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-05-23 — — US claimed
US-3989741-A ALKYLATION, REDUCTION, TRANSESTERIFICATION, ESTER-SUBSTITUTED PHENOLS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-11-02 — — US claimed
JP-10114754-A — — None — — JP disclosed
US-20230312457-A1 LOW-MIGRATION HINDERED PHENOL ANTIOXIDANT COMPOUND, PREPARATION METHOD AND COMPOSITION TSENG, JERRY (TW) 2023-10-05 — — US disclosed
US-20230312457-A1 LOW-MIGRATION HINDERED PHENOL ANTIOXIDANT COMPOUND, PREPARATION METHOD AND COMPOSITION TSENG, JERRY (TW) 2023-10-05 — — US disclosed
US-20230312457-A1 LOW-MIGRATION HINDERED PHENOL ANTIOXIDANT COMPOUND, PREPARATION METHOD AND COMPOSITION TSENG, JERRY (TW) 2023-10-05 — — US disclosed
US-3971757-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1976-07-27 — — US disclosed
US-3969316-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-13 — — US disclosed
US-3966711-A 4-Alkyl-1,4-diaza-5-oxo-cycloheptanes and their 1-oxyls CIBA-GEIGY CORPORATION (US) 1976-06-29 — — US disclosed
US-3865906-A 0,0-Dialkyl-(3,5-dialkyl-4-hydroxybenzyl)dithiophosphate compositions and process for making same ETHYL CORP 1975-02-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312457-A1 LOW-MIGRATION HINDERED PHENOL ANTIOXIDANT COMPOUND, PREPARATION METHOD AND COMPOSITION COMT, CAT, GPX4 ALDH1A1 921/4885GAA 1549/4885TSHR 4831/4885
US-20110136748-A1 NOVEL GLUCOPYRANOSE DERIVATIVES, PREPARATION THEREOF, AND BIOLOGICAL USES THEREOF GALE, UGGT1, G6PD ALDH1A1 863/4885GAA 125/4885TSHR 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.