Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807683 | 0.78 | HSD17B10 (0.39) | HSD17B10ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL1837932 | 0.77 | ALDH1A1 (0.42) | HSD17B10ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL10595738 | 0.72 | HSD17B10 (0.48) | HSD17B10ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL9584842 | 0.71 | HSD17B10 (0.41) | HSD17B10ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL9807668 | 0.70 | TDP1 (0.42) | NFKB1NFKB2RELAALDH1A1KDM4E | |
| SCHEMBL10549315 | 0.70 | NLRP3 (0.43) | HSD17B10ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL10348515 | 0.70 | HSD17B10 (0.40) | HSD17B10ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL18380884 | 0.69 | SMYD3 (0.47) | NFKB1NFKB2RELAALDH1A1KDM4E | |
| SCHEMBL7788916 | 0.69 | SMYD3 (0.47) | NFKB1NFKB2RELAALDH1A1KDM4E | |
| SCHEMBL7470486 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278907-B1 | CYCLOHEXANE DIONES | CIBA-GEIGY AG (CH) | 1991-05-29 | — | — | EP | claimed |
| US-4872902-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1989-10-10 | — | — | US | claimed |
| EP-0278907-A1 | Cyclohexane diones | CIBA-GEIGY AG (CH) | 1988-08-17 | — | — | EP | claimed |
| EP-0278907-B1 | CYCLOHEXANE DIONES | CIBA-GEIGY AG (CH) | 1991-05-29 | — | — | EP | disclosed |
| US-4872902-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0278907-A1 | Cyclohexane diones | CIBA-GEIGY AG (CH) | 1988-08-17 | — | — | EP | disclosed |