Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807692 | 0.80 | MAPT (0.41) | TDP1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL9807671 | 0.78 | ALDH1A1 (0.45) | RAB9AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL10815118 | 0.74 | SMN1; SMN2 (0.53) | TDP1KMT2AMEN1RAB9AKDM4E | |
| SCHEMBL7344969 | 0.72 | TSHR (0.50) | KDM4EMAPTALDH1A1MAPK1CYP3A4 | |
| SCHEMBL9874230 | 0.70 | P2RX7 (0.49) | KMT2AMEN1RAB9AKDM4EMAPT | |
| SCHEMBL9807672 | 0.70 | NFKB1 (0.44) | NFKB1NFKB2RELAKDM4EMAPT | |
| SCHEMBL9814786 | 0.69 | SMN1; SMN2 (0.47) | TDP1KMT2AMEN1RAB9AKDM4E | |
| SCHEMBL522136 | 0.68 | KMT2A (0.59) | TDP1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL9467111 | 0.67 | SMN1; SMN2 (0.39) | TDP1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL29364863 | 0.67 | TDP1 (0.62) | TDP1KMT2AMEN1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278907-B1 | CYCLOHEXANE DIONES | CIBA-GEIGY AG (CH) | 1991-05-29 | — | — | EP | claimed |
| US-4872902-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1989-10-10 | — | — | US | claimed |
| EP-0278907-A1 | Cyclohexane diones | CIBA-GEIGY AG (CH) | 1988-08-17 | — | — | EP | claimed |
| EP-0278907-B1 | CYCLOHEXANE DIONES | CIBA-GEIGY AG (CH) | 1991-05-29 | — | — | EP | disclosed |
| US-4872902-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0278907-A1 | Cyclohexane diones | CIBA-GEIGY AG (CH) | 1988-08-17 | — | — | EP | disclosed |