Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CPN1 | P15169 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 5/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246196 | 0.88 | MMP1 (0.36) | LTA4HMMP1MMP2CTSKREN | |
| SCHEMBL9244602 | 0.79 | LTA4H (0.43) | LTA4HMMP1CPN1CPB2 | |
| SCHEMBL9242478 | 0.77 | MMP1 (0.38) | LTA4HMMP1MMP2ATMCTSK | |
| SCHEMBL7049015 | 0.76 | MMP1 (0.37) | LTA4HMMP1MMP2ATMCTSK | |
| SCHEMBL9244187 | 0.75 | MMP1 (0.41) | LTA4HMMP1CPN1CPB2ATM | |
| SCHEMBL9246018 | 0.75 | LTA4H (0.44) | LTA4HMMP1MMP2CPN1CPB2 | |
| SCHEMBL9246101 | 0.72 | ALDH1A1 (0.41) | MMP1MMP2CTSKALDH1A1KMT2A | |
| SCHEMBL9241532 | 0.72 | ALDH1A1 (0.41) | MMP1MMP2CTSKALDH1A1KMT2A | |
| SCHEMBL13711848 | 0.71 | ATM (0.50) | LTA4HCPN1CPB2SMN1; SMN2ATM | |
| SCHEMBL2484332 | 0.71 | ATM (0.50) | LTA4HCPN1CPB2SMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988681-A | Dipeptidase inhibitore; reducing renal toxicity; prevention deactivation of (carba)penem antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | disclosed |