Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 3/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | CPN1 | P15169 | 2/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.37 |
| ▸ | DPEP1 | P16444 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646994 | 0.83 | DPEP1 (0.49) | ANPEPLAP3ERAP2DPEP1 | |
| SCHEMBL9244602 | 0.83 | LTA4H (0.43) | LTA4HANPEPLAP3CPN1CPB2 | |
| SCHEMBL9244187 | 0.81 | MMP1 (0.41) | LTA4HCPN1CPB2MMP1MMP13 | |
| SCHEMBL9647220 | 0.77 | ANPEP (0.65) | ANPEPLAP3ERAP2DPEP1 | |
| SCHEMBL9647093 | 0.77 | ALDH1A1 (0.47) | ANPEPLAP3ERAP2DPEP1 | |
| SCHEMBL8871986 | 0.77 | CPN1 (0.50) | LTA4HCPN1CPB2MMP2MMP9 | |
| SCHEMBL9243534 | 0.77 | GCLC (0.41) | LTA4HMMP1MMP13 | |
| SCHEMBL9242284 | 0.77 | LTA4H (0.38) | LTA4HCPN1CPB2DPEP1MMP1 | |
| SCHEMBL15203782 | 0.75 | CPN1 (0.48) | LTA4HCPN1CPB2MMP2MMP9 | |
| SCHEMBL9248326 | 0.75 | ALDH1A1 (0.44) | LTA4HMMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347840-B1 | Phosphinic acid derivates | BANYU PHARMA CO LTD (JP) | 1995-12-27 | — | — | EP | disclosed |
| US-4988681-A | Dipeptidase inhibitore; reducing renal toxicity; prevention deactivation of (carba)penem antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0347840-A2 | Phosphinic acid derivates | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |