Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625324 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL454855 | 0.86 | LMNA (0.52) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL9918852 | 0.84 | TSHR (0.43) | ALDH1A1TSHRSMN1; SMN2LMNACHRM1 | |
| SCHEMBL15469686 | 0.84 | TSHR (0.43) | ALDH1A1TSHRSMN1; SMN2LMNACHRM1 | |
| SCHEMBL10662128 | 0.84 | OPRM1 (0.39) | TSHRLMNAMETAP1CYP3A4CYP2D6 | |
| SCHEMBL1053416 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL30987410 | 0.81 | OPRM1 (0.38) | TSHRLMNACYP3A4CYP2D6SPHK1 | |
| SCHEMBL4444621 | 0.81 | DNM1 (0.39) | ALDH1A1TSHRSMN1; SMN2LMNATDP1 | |
| SCHEMBL7205723 | 0.81 | LMNA (0.59) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL727391 | 0.81 | LMNA (0.59) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994496-A | Contact lens and silicone contact lens | 望隼科技股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-119002096-A | Method for manufacturing contact lens | 望隼科技股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-116983695-A | Device and method for by-producing isovaleraldehyde by utilizing oil phase of condensation circulating tower of 2-propylheptanol production device | 中国海洋石油集团有限公司 | 2023-11-03 | — | — | CN | disclosed |
| US-20120122947-A1 | SPIRO-OXINDOLE MDM2 ANTAGONISTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-05-17 | — | — | US | disclosed |
| US-20110001221-A1 | DIELECTRIC LAYER | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2011-01-06 | — | — | US | disclosed |
| US-7829137-B2 | Fabricating dielectric layer | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-11-09 | — | — | US | disclosed |
| US-20080249606-A1 | Methods for Determining the Effect of a Treatment on the Cross-Beta Structure Content of a Protein; Selection of Treatments and Uses Thereof | CROSSBETA BIOSCIENCES B.V. (NL) | 2008-10-09 | — | — | US | disclosed |
| JP-2007238573-A | PERFUME USED IN FIRST AGENT OF TWO-PACK TYPE OXIDATION HAIRDYE, AND THE FIRST AGENT OF THE TWO-PACK TYPE OXIDATION HAIRDYE CONTAINING THE PERFUME | OGAWA & CO LTD | 2007-09-20 | — | — | JP | disclosed |
| US-20070172583-A1 | DIELECTRIC LAYER, COMPOSITION AND METHOD FOR FORMING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122947-A1 | SPIRO-OXINDOLE MDM2 ANTAGONISTS | TP53, MDM2, TP53BP1 | ALDH1A1 1498/4885TSHR 2230/4885SMN1; SMN2 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.