Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.52 |
| ▸ | YAP1 | P46937 | 1/20 | 0.52 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.52 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808195 | 0.92 | HTT (0.52) | HTTALDH1A1LMNATEAD1YAP1 | |
| SCHEMBL9808177 | 0.87 | HTT (0.59) | HTTALDH1A1LMNATEAD1YAP1 | |
| SCHEMBL9808060 | 0.83 | ALDH1A1 (0.53) | HTTALDH1A1LMNATEAD1YAP1 | |
| SCHEMBL9808079 | 0.81 | HPGD (0.51) | HTTALDH1A1TEAD1YAP1TEAD4 | |
| SCHEMBL9808182 | 0.80 | MAPT (0.53) | HTTALDH1A1LMNAMAPTGAA | |
| SCHEMBL9808246 | 0.79 | ALDH1A1 (0.66) | HTTALDH1A1LMNATEAD1YAP1 | |
| SCHEMBL9808286 | 0.78 | HTT (0.56) | HTTALDH1A1LMNATEAD1YAP1 | |
| SCHEMBL9808044 | 0.78 | TDP1 (0.51) | HTTTEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL9808214 | 0.78 | HTT (0.48) | HTTALDH1A1LMNATEAD1YAP1 | |
| SCHEMBL9808292 | 0.75 | BCL2L11 (0.38) | HTTALDH1A1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |