Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BCL2L11 | O43521 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808292 | 0.92 | BCL2L11 (0.38) | TDP1L3MBTL1ALDH1A1BCL2L11BCL2L1 | |
| SCHEMBL9808202 | 0.87 | APP (0.41) | TDP1L3MBTL1ALDH1A1HTTPKM | |
| SCHEMBL9808284 | 0.83 | ATM (0.38) | TDP1L3MBTL1BCL2L11BCL2L1MCL1 | |
| SCHEMBL9808197 | 0.81 | MAPT (0.38) | TDP1L3MBTL1CYP19A1CA2HTT | |
| SCHEMBL9808190 | 0.81 | HDAC6 (0.49) | TDP1ALDH1A1HTTMEN1RAB9A | |
| SCHEMBL9808205 | 0.79 | HSP90AA1 (0.42) | TDP1L3MBTL1ALDH1A1CA2HTT | |
| SCHEMBL9750096 | 0.78 | THRB (0.45) | TDP1THRBCYP19A1CA2MEN1 | |
| SCHEMBL9808053 | 0.78 | APP (0.43) | ALDH1A1BCL2L11BCL2L1MCL1CA2 | |
| SCHEMBL9808327 | 0.78 | TSHR (0.41) | TDP1L3MBTL1THRBCYP19A1CA2 | |
| SCHEMBL9808195 | 0.77 | HTT (0.52) | TDP1ALDH1A1CA2HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |