Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554829 | 0.93 | CA2 (0.50) | THRBTSHRHSD17B10CYP19A1HDAC3 | |
| SCHEMBL9143375 | 0.92 | THRB (0.55) | THRBCYP19A1CA2CA1 | |
| SCHEMBL3719385 | 0.83 | CA2 (0.43) | THRBTSHRHSD17B10CYP19A1CA2 | |
| SCHEMBL9808044 | 0.81 | TDP1 (0.51) | THRBHSD17B10CYP19A1HDAC3HDAC4 | |
| SCHEMBL9808068 | 0.78 | TDP1 (0.38) | THRBCYP19A1CA2TDP1MEN1 | |
| SCHEMBL3723662 | 0.78 | HSD17B10 (0.50) | TSHRHSD17B10CYP19A1CA2CA1 | |
| SCHEMBL9808327 | 0.78 | TSHR (0.41) | THRBTSHRHSD17B10CYP19A1CA2 | |
| SCHEMBL9808079 | 0.77 | HPGD (0.51) | HSD17B10HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9808195 | 0.77 | HTT (0.52) | HSD17B10CA2CA1TDP1KMT2A | |
| SCHEMBL9750261 | 0.77 | ESR1 (0.44) | THRBCA2TDP1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126486-A | Color developers for leuco dyes in thermal printing | RICOH COMPANY, LTD. (JP) | 1992-06-30 | — | — | US | disclosed |
| US-4978651-A | With a colorless or light colored leuco dye for inducing color formation | RICOH COMPANY, LTD. (JP) | 1990-12-18 | — | — | US | disclosed |