⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404054 | 0.81 | — | — | |
| SCHEMBL9808623 | 0.79 | — | — | |
| SCHEMBL420577 | 0.78 | ALDH1A1 (0.40) | — | |
| SCHEMBL4304520 | 0.75 | TP53 (0.37) | — | |
| SCHEMBL9253272 | 0.72 | PPM1B (0.34) | — | |
| SCHEMBL9253268 | 0.72 | — | — | |
| SCHEMBL9808685 | 0.71 | — | — | |
| SCHEMBL8034384 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL9564946 | 0.70 | LMNA (0.52) | — | |
| SCHEMBL9257533 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230347-B1 | MACROLIDE COMPOUNDS, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-15 | — | — | EP | claimed |
| US-4912090-A | Antiparasitic milbemycin and avermectin derivatives | SANKYO COMPANY LIMITED (JP) | 1990-03-27 | — | — | US | claimed |
| EP-0230347-A1 | Macrolide compounds, their preparation and use | Sankyo Company Limited (JP) | 1987-07-29 | — | — | EP | claimed |
| CN-1021910-C | LANKACIDIN DERIVATIVES AND PRODUCTION THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-08-25 | — | — | CN | disclosed |
| US-4912090-A | Antiparasitic milbemycin and avermectin derivatives | SANKYO COMPANY LIMITED (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0230347-A1 | Macrolide compounds, their preparation and use | Sankyo Company Limited (JP) | 1987-07-29 | — | — | EP | disclosed |