Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | MTOR | P42345 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504257 | 1.00 | TRPV1 (0.70) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL504255 | 1.00 | TRPV1 (0.70) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL29380151 | 1.00 | TRPV1 (0.70) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL1586047 | 0.98 | TRPV1 (0.67) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL1585893 | 0.93 | TRPV1 (0.61) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL29530847 | 0.93 | TRPV1 (0.74) | TRPV1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28755565 | 0.93 | TRPV1 (0.74) | TRPV1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9808706 | 0.93 | TRPV1 (0.74) | TRPV1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL258429 | 0.93 | TRPV1 (0.74) | TRPV1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL155980 | 0.87 | TRPV1 (0.85) | TRPV1MAPTHPGDMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206609-B1 | COMPOUNDS AND COMPOSITIONS HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | THE PROCTER & GAMBLE COMPANY (US) | 1989-09-20 | — | — | EP | claimed |
| EP-0206609-A1 | Compounds and compositions having anti-inflammatory and analgesic activity | THE PROCTER & GAMBLE COMPANY (US) | 1986-12-30 | — | — | EP | claimed |
| US-5013759-A | Phenylacetic acid amide or thioamide derivatives | THE PROCTER & GAMBLE COMPANY (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0206609-B1 | COMPOUNDS AND COMPOSITIONS HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | THE PROCTER & GAMBLE COMPANY (US) | 1989-09-20 | — | — | EP | disclosed |
| EP-0206609-A1 | Compounds and compositions having anti-inflammatory and analgesic activity | THE PROCTER & GAMBLE COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |