SCHEMBL258429

SCHEMBL258429

CCCCCCCCNC(=O)Cc1ccc(O)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 1/20 0.74
▸ ALDH1A1 P00352 1/20 0.66
▸ CYP1A2 P05177 1/20 0.66
▸ CYP3A4 P08684 1/20 0.66
▸ CYP2D6 P10635 1/20 0.66
▸ CYP2C9 P11712 1/20 0.66
▸ HPGD P15428 1/20 0.66
▸ ALOX15 P16050 1/20 0.66
▸ CYP2C19 P33261 1/20 0.66
▸ BLM P54132 1/20 0.66
▸ PMP22 Q01453 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28755565 1.00 TRPV1 (0.74) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL29530847 1.00 TRPV1 (0.74) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL9808706 1.00 TRPV1 (0.74) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL29380151 0.93 TRPV1 (0.70) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL504255 0.93 TRPV1 (0.70) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL504257 0.93 TRPV1 (0.70) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL9808674 0.93 TRPV1 (0.70) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL9808719 0.92 ALDH1A1 (0.64) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL1586047 0.91 TRPV1 (0.67) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL29530867 0.90 L3MBTL1 (0.73) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1517880-B1 PRODUCTION OF CIS-PELLITORIN AND USE AS A FLAVOURING SYMRISE AG (DE) 2011-01-05 — — EP claimed
US-20260041109-A1 ROBUST FLAVOR EMULSIONS INT FLAVORS & FRAGRANCES INC (US) 2026-02-12 — — US disclosed
US-12419815-B2 Microcapsule compositions stabilized with viscosity control agents INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-09-23 — — US disclosed
EP-4615958-A1 CELL COMPOSITIONS Givaudan SA (CH) 2025-09-17 — — EP disclosed
US-12357547-B2 Compositions containing microcapsules INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-07-15 — — US disclosed
US-12324452-B2 Delivery systems and methods of preparing the same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-06-10 — — US disclosed
US-12274771-B2 Polyurea capsule compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-04-15 — — US disclosed
US-12030326-B2 System and method for printing and drying flavors and fragrances INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2024-07-09 — — US disclosed
US-20240180220-A1 HYDROGEL ENCAPSULATIONS AND METHODS OF MAKING THE SAME INTERNATIONAL FLAVORS & FRANGRANCES INC. 2024-06-06 — — US disclosed
WO-2024100137-A1 CELL COMPOSITIONS GIVAUDAN SA (CH) 2024-05-16 — — WO disclosed
EP-1761271-A1 BLACKBERRY EXTRACT Symrise GmbH & Co. KG (DE) 2007-03-14 — — EP disclosed
WO-2006032668-A1 USE OF AROMA SUBSTANCE MIXTURES AS AGENTS AGAINST BAD BREATH SYMRISE GMBH & CO. KG (DE) 2006-03-30 — — WO disclosed
WO-2006032667-A1 USE OF BETA-HOMOCYCLOCITRAL AS AN AGENT AGAINST BAD BREATH SYMRISE GMBH & CO. KG (DE) 2006-03-30 — — WO disclosed
WO-2005123101-A1 BLACKBERRY EXTRACT SYMRISE GMBH & CO. KG (DE) 2005-12-29 — — WO disclosed
US-20050244561-A1 Carvone acetals used as flavourings SYMRISE GMBH & CO. KG (DE) 2005-11-03 — — US disclosed
US-20050234132-A1 Production of cis-pellitorin and use as a flavouring SYMRISE AG (DE) 2005-10-20 — — US disclosed
US-20050208084-A1 Use of alkylamidomandelates as flavourings SYMRISE GMBH & CO. KG (DE) 2005-09-22 — — US disclosed
US-20040241312-A1 Use of 2E,4E-decadienoic acid isobutylamide for imparting a salivation inducing effect to a foodstuff, an oral hygiene preparation or a gourmet or snack preparation; preparation by amidating a dodecadienoate with isobutylamine SYMRISE AG (DE) 2004-12-02 — — US disclosed
US-6673756-B2 MULTILAYER; CUTTING, JOINING UNDER PRESSURE SYMRISE GMBH & CO. KG (DE) 2004-01-06 — — US disclosed
US-20020173436-A1 Multilayer; cutting, joining under pressure SYMRISE GMBH & CO. KG (DE) 2002-11-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12357547-B2 Compositions containing microcapsules COPE, SAAL1, AUP1 TRPV1 4192/4885ALDH1A1 4610/4885CYP1A2 4690/4885
US-12324452-B2 Delivery systems and methods of preparing the same MAL2, TAS2R42, TAS2R31 TRPV1 749/4885ALDH1A1 378/4885CYP1A2 414/4885
US-20050234132-A1 Production of cis-pellitorin and use as a flavouring NISCH, CYP8B1, DLAT TRPV1 1061/4885ALDH1A1 429/4885CYP1A2 76/4885
US-20050208084-A1 Use of alkylamidomandelates as flavourings HNMT, TAS2R7, PNMT TRPV1 308/4885ALDH1A1 807/4885CYP1A2 549/4885
US-12419815-B2 Microcapsule compositions stabilized with viscosity control agents ACR, ALG1, MLEC TRPV1 3271/4885ALDH1A1 4627/4885CYP1A2 4836/4885
US-12274771-B2 Polyurea capsule compositions PUF60, UMPS, PCBP1 TRPV1 3537/4885ALDH1A1 4096/4885CYP1A2 4802/4885
US-20260041109-A1 ROBUST FLAVOR EMULSIONS ACACA, FABP4, CUTA TRPV1 687/4885ALDH1A1 362/4885CYP1A2 2577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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