Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | MTOR | P42345 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808674 | 1.00 | TRPV1 (0.70) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL504257 | 1.00 | TRPV1 (0.70) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL29380151 | 1.00 | TRPV1 (0.70) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL1586047 | 0.98 | TRPV1 (0.67) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL1585893 | 0.93 | TRPV1 (0.61) | TRPV1MAPTHPGDMEN1TP53 | |
| SCHEMBL29530847 | 0.93 | TRPV1 (0.74) | TRPV1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28755565 | 0.93 | TRPV1 (0.74) | TRPV1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9808706 | 0.93 | TRPV1 (0.74) | TRPV1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL258429 | 0.93 | TRPV1 (0.74) | TRPV1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL155980 | 0.87 | TRPV1 (0.85) | TRPV1MAPTHPGDMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1736485-A | Use of vanillin receptor agonist in preparation of product for resisting Alzheimer disease | SHANGHAI MEDICILON INC (CN) | 2006-02-22 | — | — | CN | claimed |
| US-20030082249-A1 | Compositions containing capsaicin and its derivatives, and their use in treating mucositis | OVATION PHARMACEUTICALS | 2003-05-01 | — | — | US | claimed |
| US-5762963-A | DISPERSING IN SOLID OR GEL VEHICLE IN WHICH CONCENTRATION OF CAPSAICINOID DECREASES FROM CENTER TOWARD PERIPHERY; FOR MOUTH, THROAT PAIN RELIEF | EMORY UNIVERSITY (US) | 1998-06-09 | — | — | US | claimed |
| WO-1996040079-A1 | METHOD AND COMPOSITIONS FOR CONTROLLING ORAL AND PHARYNGEAL PAIN USING CAPSAICINOIDS | EMORY UNIVERSITY (US) | 1996-12-19 | — | — | WO | claimed |
| US-5013759-A | Phenylacetic acid amide or thioamide derivatives | THE PROCTER & GAMBLE COMPANY (US) | 1991-05-07 | — | — | US | claimed |
| EP-0206609-B1 | COMPOUNDS AND COMPOSITIONS HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | THE PROCTER & GAMBLE COMPANY (US) | 1989-09-20 | — | — | EP | claimed |
| EP-0206609-A1 | Compounds and compositions having anti-inflammatory and analgesic activity | THE PROCTER & GAMBLE COMPANY (US) | 1986-12-30 | — | — | EP | claimed |
| EP-3938345-B1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | NOCION THERAPEUTICS INC (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20260116859-A1 | Charged Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260060989-A1 | Charged Ion Channel Blockers And Methods For Use | NOCION THERAPEUTICS INC (US) | 2026-03-05 | — | — | US | disclosed |
| US-20250270189-A1 | Ester Substituted Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2025-08-28 | — | — | US | disclosed |
| US-20250263375-A1 | Charged Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2025-08-21 | — | — | US | disclosed |
| US-20250263386-A1 | Charged Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2025-08-21 | — | — | US | disclosed |
| EP-0282127-B1 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | PROCTER & GAMBLE (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5099030-A | Phenols or phenolic ethers | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045565-A | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain | THE PROCTER & GAMBLE COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| US-5013759-A | Phenylacetic acid amide or thioamide derivatives | THE PROCTER & GAMBLE COMPANY (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0206609-B1 | COMPOUNDS AND COMPOSITIONS HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | THE PROCTER & GAMBLE COMPANY (US) | 1989-09-20 | — | — | EP | disclosed |
| EP-0282127-A2 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | THE PROCTER & GAMBLE COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0206609-A1 | Compounds and compositions having anti-inflammatory and analgesic activity | THE PROCTER & GAMBLE COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250263386-A1 | Charged Ion Channel Blockers and Methods for Use | TRPV1, TRPV5, TRPV2 | TRPV1 1/4885MAPT 2578/4885HPGD 1583/4885 |
| US-20250263375-A1 | Charged Ion Channel Blockers and Methods for Use | TRPV1, TRPV2, TRPV5 | TRPV1 1/4885MAPT 1799/4885HPGD 1754/4885 |
| US-20260060989-A1 | Charged Ion Channel Blockers And Methods For Use | TRPV1, TRPA1, TRPV2 | TRPV1 1/4885MAPT 1178/4885HPGD 3470/4885 |
| US-20260116859-A1 | Charged Ion Channel Blockers and Methods for Use | OPRL1, TRPV1, SCN2B | TRPV1 2/4885MAPT 3147/4885HPGD 2311/4885 |
| US-20250270189-A1 | Ester Substituted Ion Channel Blockers and Methods for Use | TRPV1, TRPA1, TRPV2 | TRPV1 1/4885MAPT 2258/4885HPGD 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.