Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258429 | 1.00 | TRPV1 (0.74) | TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29530847 | 1.00 | TRPV1 (0.74) | TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9808706 | 1.00 | TRPV1 (0.74) | TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29380151 | 0.93 | TRPV1 (0.70) | TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL504255 | 0.93 | TRPV1 (0.70) | TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL504257 | 0.93 | TRPV1 (0.70) | TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9808674 | 0.93 | TRPV1 (0.70) | TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9808719 | 0.92 | ALDH1A1 (0.64) | TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1586047 | 0.91 | TRPV1 (0.67) | TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29530867 | 0.90 | L3MBTL1 (0.73) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315631-B | Capsaicin derivative, and preparation method and application thereof | 广西医科大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-114315631-A | Capsaicin derivative and preparation method and application thereof | 广西医科大学 | 2022-04-12 | — | — | CN | disclosed |