Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507595 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4623856 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL7562427 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL9808905 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TDP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL9808915 | 0.77 | PDGFRB (0.53) | ALDH1A1TDP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL25295556 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL26832242 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL6309234 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL27986575 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL9808908 | 0.75 | LMNA (0.50) | ALDH1A1MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |