Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452552 | 0.83 | HCAR3 (0.54) | HCAR3MAPTGAAALDH1A1KMT2A | |
| SCHEMBL9808933 | 0.79 | MAPT (0.41) | LMNAMAPTGAAALDH1A1HTT | |
| SCHEMBL9808912 | 0.79 | LMNA (0.54) | LMNAHCAR3MAPTGAAALDH1A1 | |
| SCHEMBL10507595 | 0.78 | ALDH1A1 (0.51) | LMNAMAPTGAAALDH1A1KMT2A | |
| SCHEMBL9808911 | 0.75 | ALDH1A1 (0.50) | LMNAMAPTALDH1A1ABCB1KMT2A | |
| SCHEMBL9808916 | 0.75 | HCAR3 (0.56) | LMNAHCAR3MAPTGAAALDH1A1 | |
| SCHEMBL27989081 | 0.74 | MAPT (0.43) | LMNAHCAR3MAPTGAAALDH1A1 | |
| SCHEMBL27471431 | 0.74 | MAPT (0.64) | LMNAHCAR3MAPTGAAALDH1A1 | |
| SCHEMBL13206258 | 0.72 | HCAR3 (0.51) | HCAR3MAPTGAAALDH1A1ABCB1 | |
| SCHEMBL162875 | 0.71 | KAT2B (0.60) | LMNAHCAR3MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4956007-A | Nitraminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYOR RT. (HU) | 1990-09-11 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |