Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808908 | 0.79 | LMNA (0.50) | MAPTALDH1A1GAAHTTLMNA | |
| SCHEMBL9808939 | 0.77 | KDM4E (0.45) | MAPTKDM4EALDH1A1GAATHRB | |
| SCHEMBL9808905 | 0.72 | ALDH1A1 (0.42) | MAPTALDH1A1GAATHRBHTT | |
| SCHEMBL9808943 | 0.72 | GAA (0.48) | MAPTKDM4EALDH1A1GAATHRB | |
| SCHEMBL14878651 | 0.66 | GAA (0.58) | MAPTKDM4EALDH1A1GAATHRB | |
| SCHEMBL3289155 | 0.66 | HPRT1 (0.40) | MAPTKDM4EALDH1A1HPGDHTT | |
| SCHEMBL29922726 | 0.66 | MAPT (0.47) | MAPTKDM4EALDH1A1GAATHRB | |
| SCHEMBL650708 | 0.66 | MAPT (0.47) | MAPTKDM4EALDH1A1GAATHRB | |
| SCHEMBL10452552 | 0.65 | HCAR3 (0.54) | MAPTALDH1A1GAA | |
| SCHEMBL11543987 | 0.65 | MAPT (0.56) | MAPTKDM4EALDH1A1GAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |