Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808917 | 0.81 | HTR2B (0.41) | PLA2G7CYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL2807338 | 0.77 | CYP3A4 (0.65) | PLA2G7CYP3A4NFKB1PMP22TSHR | |
| SCHEMBL9808964 | 0.74 | HSD17B10 (0.50) | CYP3A4NFKB1PMP22TSHRSMN1; SMN2 | |
| SCHEMBL9808975 | 0.70 | CYP3A4 (0.42) | PLA2G7CYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9808986 | 0.70 | CYP3A4 (0.42) | PLA2G7CYP3A4NFKB1PMP22TSHR | |
| SCHEMBL13365533 | 0.70 | CYP2A6 (0.54) | PLA2G7CYP3A4NFKB1PMP22TSHR | |
| SCHEMBL9006034 | 0.70 | PLA2G7 (0.69) | PLA2G7CYP3A4NFKB1PMP22TSHR | |
| SCHEMBL31374861 | 0.70 | CYP2A6 (0.54) | PLA2G7CYP3A4NFKB1PMP22TSHR | |
| SCHEMBL31607633 | 0.69 | PLA2G7 (0.49) | PLA2G7CYP3A4NFKB1PMP22TSHR | |
| SCHEMBL27185966 | 0.69 | PLA2G7 (0.49) | PLA2G7CYP3A4NFKB1PMP22TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |