Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021636 | 0.76 | ESR2 (0.50) | CYP3A4TSHRPLA2G7CA1CA2 | |
| SCHEMBL21021252 | 0.76 | PLA2G7 (0.50) | CYP3A4TSHRPLA2G7USP28AHR | |
| SCHEMBL13365533 | 0.75 | CYP2A6 (0.54) | CYP3A4TSHRPLA2G7ALDH1A1SMN1; SMN2 | |
| SCHEMBL31374861 | 0.75 | CYP2A6 (0.54) | CYP3A4TSHRPLA2G7ALDH1A1SMN1; SMN2 | |
| SCHEMBL9808973 | 0.73 | HSD17B10 (0.51) | CYP3A4ALDH1A1HSD17B10MAPTKDM4E | |
| SCHEMBL2807338 | 0.73 | CYP3A4 (0.65) | CYP3A4TSHRPLA2G7CA1CA2 | |
| SCHEMBL14744471 | 0.72 | IMPDH2 (0.49) | CYP3A4TSHRPLA2G7ALDH1A1SMN1; SMN2 | |
| SCHEMBL12458455 | 0.71 | ALDH1A1 (0.47) | CYP3A4TSHRPLA2G7USP28AHR | |
| SCHEMBL9629264 | 0.71 | HTR2B (0.50) | CYP3A4TSHRUSP28AHRALDH1A1 | |
| SCHEMBL310582 | 0.71 | MEN1 (0.50) | CYP3A4TSHRCA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |