Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTPRC | P08575 | 3/20 | 0.47 |
| ▸ | S100A4 | P26447 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452388 | 0.84 | HSD17B10 (0.49) | HSD17B10PTPRCS100A4NPBWR1MAPT | |
| SCHEMBL27652680 | 0.76 | HSD17B10 (0.58) | HSD17B10PTPRCS100A4BCHEACHE | |
| SCHEMBL9808965 | 0.74 | PLA2G7 (0.49) | PTPRCS100A4MAPTHSP90AA1CDK5 | |
| SCHEMBL9808973 | 0.74 | HSD17B10 (0.51) | HSD17B10PTPRCS100A4BCHEACHE | |
| SCHEMBL9808985 | 0.74 | HSD17B10 (0.51) | HSD17B10NPBWR1MAPTVCAM1PDE7A | |
| SCHEMBL16620979 | 0.74 | KMT2A (0.61) | HSD17B10PTPRCS100A4BCHEACHE | |
| SCHEMBL11165999 | 0.72 | MAPT (0.50) | HSD17B10PTPRCS100A4BCHEACHE | |
| SCHEMBL10452725 | 0.72 | ALDH1A1 (0.55) | HSD17B10PTPRCS100A4MEN1KMT2A | |
| SCHEMBL14746574 | 0.71 | HSD17B10 (0.45) | HSD17B10PTPRCS100A4BCHEACHE | |
| SCHEMBL10452131 | 0.71 | TDP1 (0.42) | HSD17B10PTPRCS100A4NPBWR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |