Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469386 | 0.87 | TDP1 (0.43) | CYP3A4SMN1; SMN2TSHRTDP1ALOX15 | |
| SCHEMBL11193057 | 0.83 | ALDH1A1 (0.57) | CYP3A4SMN1; SMN2TSHRTDP1ALOX15 | |
| SCHEMBL9808892 | 0.82 | ALOX15 (0.36) | CYP3A4SMN1; SMN2TSHRTDP1ALOX15 | |
| SCHEMBL10505528 | 0.80 | TDP1 (0.52) | CYP3A4SMN1; SMN2TSHRTDP1ALOX15 | |
| SCHEMBL10507644 | 0.80 | ALDH1A1 (0.40) | CYP3A4SMN1; SMN2TSHRTDP1ALOX15 | |
| SCHEMBL9637022 | 0.80 | LMNA (0.50) | CYP3A4TSHRTDP1ALOX15ALDH1A1 | |
| SCHEMBL9635796 | 0.80 | LMNA (0.50) | CYP3A4TSHRTDP1ALOX15ALDH1A1 | |
| SCHEMBL548628 | 0.80 | LMNA (0.50) | CYP3A4TSHRTDP1ALOX15ALDH1A1 | |
| SCHEMBL10923598 | 0.79 | MEN1 (0.50) | CYP3A4SMN1; SMN2TSHRTDP1ALOX15 | |
| SCHEMBL10451346 | 0.78 | TDP1 (0.50) | CYP3A4TSHRTDP1ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |